Q: First tests in acute monoarthritis A: Joint aspiration and synovial fluid analysis Q: Diseases characterized by inflammation of axial skeleton, enthesitis, positive HLA-B27 A: Spondyloarthritis (ankylosing spondylitis, psoriatic arthrit…

Q: Positive bronchial challenge test result A: ≥ 20% FEV1 reduction (vs At least 12% increase in FEV1 after bronchodilator) Q: Diagnosis suggested by TLC < 80% of predicted A: Restrictive lung disease (Obstructive disease: FEV1/FVC ration …

Q: Preferred term for “progression-free survival” A: “Progression-free interval” The time from when a Tx is started until that Tx is no longer controlling the cancer Q: Checkpoint inhibitor toxicity A: Autoimmune disease Checkpoint inhibit…

Q: Red flags for secondary headache A: Focal neurologic findings, worst/progressive headache, new headache after age 50 years, thunderclap headache, onset after exertion Q: Imaging for reversible cerebral vasoconstriction syndrome A: Brain…

Q: Common medications that decrease creatinine secretion A: Cimetidine, trimethoprim Q: Preferred marker of glomerular filtration when creatinine is likely inaccurate A: Cystatin C Q: Urine dipstick positive for blood, no RBCs in sediment …

Q: Most common cause of recurrent viral meningitis A: HSV-2 (1: encephalitis, 2: meningitis) Q: Neisseria not covered by quadrivalent meningococcal vaccine A: Serogroup B N. Meningitides serogroups (A, B, C, Y, W-135) (B,C,Y common in US) …

Q: Isolated mild asymptomatic neutropenia in a patient of African descent A: Benign ethnic neutropenia (Duffy-null associated neutrophil count (DANC), not increase risk of infection) Q: Treatment to shorten recovery time in drug-induced ne…

Q: Lead-time bias A: Survival time appears longer because the screened patient was diagnosed earlier Q: Length-time bias A: Survival time appears longer because screening detects indolent disease Q: Indication for one-time abdominal aortic…

Q: Study type providing the highest level of evidence A: Systematic review Q: Strongest clinical study design A: Randomized controlled trial Q: Increase in disease probability with positive LRs of 2, 5, and 10 A: 15%, 30%, and 45% Q: Numbe…

Q: DM diagnostic tests A: HgbA1c (>6.5), FBG (>126), OGTT (2h>200); random glucose if hyperglycemic symptoms Q: T1DM antibody testing in new diagnosis A: GAD (Glutamic acid decarboxylase) Q: Diseases associated with acanthosis nigricans A:…

Q: Diagnosis suggested by dysphagia, late regurgitation of undigested food A: Pharyngoesophageal (Zenker) diverticulum Q: Test for oropharyngeal dysphagia A: Modified barium swallow and video fluoroscopy Q: Diagnosis suggested by dysphagia…

Q: Optimal pretest probability of CAD for stress testing A: Intermediate (10%-90%) Q: Baseline ECG abnormalities that warrant imaging along with stress testing A: ST segment depression, LVH, LBBB, digitalis effect, preexcitation, paced bea…

Tx for patient with Behcet syndrome having mucocutaneous ulceration refractory to colchicine -> Apremilast (phospodiesterase-4 inhibitor) Management of 23 yo M developing fever, abd pain, rash, and arthritis of R knee of 3 days and resolve…

Management of 53 yo F incidentally found 4mm solid lung nodule, no other nodule, no lymphadenopathy, no personal or family history of lung cancer, lifelong nonsmoker -> No further follow-up (patient is low risk and nodule < 6mm -> require …

Pretreatment of imaging of 52 yo F found to have 1.8 cm breast mass, confirmed as invasive ductal carcinoma by biopsy, asymptomatic, labs all normal, no adenopathy in physical exam -> None (imaging studies for staging are not recommended i…

Management of 25 yo male with h/o mild TBI from military duty having persistent posttraumatic headaches without neurological impairment -> Screen for depression (susceptible to PTSD and depression) Management of patient with MS having diff…

Does Respiratory alkalosis cause hypokalemia? ->yes (What causes hypokalemia in asthmatic patients? -> albuterol (> respiratory alkalosis)) Management of 69 yo male who was recently diagnosed with membranous nephropathy -> Evaluation for S…

Tx for pharyngeal gonorrhea -> single dose of ceftriaxone IM To prevent HIV transmission from patient with monogamous relationship, consistently taking ART and achieving viral suppression -> no additional preventive strategy necessary Dx a…

Evaluation of smoldering multiple myeloma -> whole-body CT scan, then whole-body MRI if CT negative. If lesion > 5mm found, considered to have MM requiring Tx Tx for pure red cell aplasia caused by parovovirus viremia -> IV immune globulin…

Tx for severe hidradenitis suppurativa -> adalimumab (inflammatory skin disorder of the apocrine glands, painful lumps, abscess, scarring in areas where skin rubs together) Management of patient who received live attenuated herpes zoster v…

Lipid management of 44 yo woman with only T2DM -> moderate-intensity statin (regardless of calculated ASCVD risk) (aged 40-75) Risk mitigation step before refilling opioid prescription -> review the state prescription monitoring database A…

Tx of autoimmune pancreatitis -> high dose prednisone Dx of 45 yo female with Elevated ALP and pruritus -> primary biliary cholangitis (formerly primary biliary cirrhosis) -> intrahepatic small bile ducts vs primary sclerosing cholangitis …

What is Dulaglutide -> glucose-like peptide 1 receptor agonist for T2DM with CV risk, weight loss Side effect of Opioid -> cause hypogonadism Med names of GLP-1R -> dulaglutide, Liraglutide, (injectable)semaglutide med names of SGLT2 -> em…

Management of Symptomatic sinus bradycardia -> pacemaker if no reversible cause Evaluation for acute chest pain in ED with negative D-dimer, and nonspecific EKG ->Coronary CT angiography in ED Dx of patient with holosyctolic murmur at the …